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Objective: To investigate the clinicopathology andDNA ploidy of gastric mucosa associated lymphoidtissue (MALT) lymphoma infiltraving the leiomyomas ofthe uterus of a patient. Methods: The routine paraffinslides were cut, stained with HE, immunochcmically byABC methodusing the and stained by Feulgen method.Then the DNA ploidy of tumor cells was measured withan image cytometer. Results: In the mucosa, submucosaand the smooth muscle layer of the stomach and in theleiomyomas of the uterus there was diffusive and denseinfiltration of centrocyte-like cells. The DNAmeasurement results were that the distribution of DNAmass of lymphoma cells in stomach and in lymph nodeshad a single main aneuploidy peak each, and thedistribution of DNA mass of lymphoma cells inleiomyomas of uterus had two peaks: one of them wasthe diploid, the other aneuploid. Conclusion: The MALTlymphoma cell invasion in uterus must be differentiatedwith a primary lymphoma in the uterus, the chroniclymphocyte Icukemia in uterus and an endometrialstromal sarcoma. The present prognosis of the patientunder discussion was poor. The follow-up resultsindicated the DNA index seemed to be important forpredicting the malignancy degree and prognosis.
Objective: To investigate the clinicopathology and DNA ploidy of gastric mucosa associated lymphoidtissue (MALT) lymphoma infiltraving the leiomyomas of the uterus of a patient. Methods: The routine paraffinslides were cut, stained with HE, immunochcmically byABC method using the and stained by Feulgen method.Then the DNA ploidy of tumor cells was measured with an image cytometer. Results: In the mucosa, submucosaand the smooth muscle layer of the stomach and in the leiomyomas of the uterus there was diffusive and denseinfiltration of centrocyte-like cells. The DNAmeasurement results were that the distribution of DNAmass of lymphoma cells in stomach and in lymph nodeshad a single main aneuploidy peak each, and thedistribution of DNA mass of lymphoma cells inleiomyomas of uterus had two peaks: one of them wasthe diploid, the other aneuploid.Continuing: The MALT lymphoma cell invasion in uterus Must be differentiatedwith a primary lymphoma in the uterus, the chroniclymphocyte Icukemia in uter Us and an endometrialstromal sarcoma. The present prognosis of the patientunder discussion was poor. The follow-up resultsindicated the DNA index seemed to be important forpredicting the malignancy degree and prognosis.