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获得性细胞免疫系统功能障碍综合征的特征是淋巴细胞减少,T淋巴细胞功能缺陷和辅助T细胞/抑制T细胞比率倒转。并伴有机会性感染和恶性肿瘤的危险性增加。这种获得性免疫缺陷综合征(AIDS)的致病因子尚未确定。本文报告2例无症状血友病患者发生弥漫性淋巴结肿大,其性质与AIDS非常相似。例1:男性、32岁,患严重血友病甲,因子Ⅷ浓度<0.01u/ml,1980年~1981年间共用5,680u因子Ⅷ浓缩物治疗。1982年4月发现有淋巴结肿大。观察数月而无症状。抗HBs和抗HBc阳性,但无肝炎临床表现。与AIDS患者无接触史。体检发现双侧颈、耳后、枕、锁骨上、腋下和腹股沟区均有淋巴结
Acquired cell immune system dysfunction syndrome is characterized by lymphopenia, T lymphocyte dysfunction and helper T cell / suppressor T cell ratio reversal. Accompanied by an increased risk of opportunistic infections and malignancies. The pathogenicity of this Acquired Immune Deficiency Syndrome (AIDS) has not been established. This article reports 2 cases of asymptomatic hemophilia in patients with diffuse lymphadenopathy, its nature and AIDS are very similar. Example 1: Male, 32 years old, suffering from severe hemophilia A, factor Ⅷ concentration <0.01u / ml, 5,680u Factor Ⅷ concentrate was used during 1980-1981. In 1982 April found swollen lymph nodes. Observed for several months without symptoms. Anti-HBs and anti-HBc positive, but no clinical manifestations of hepatitis. No history of contact with AIDS patients. Physical examination found bilateral neck, ear, pillow, supraclavicular, armpit and groin area have lymph nodes