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目的:1995年在蚌埠地区开展了第2次糖尿病(diabetes mellitus,DM)流行病学普查,10年间,扩大DM三级防治网,提高防治水平。方法:指导1995年2282人中普查出的60例T2DM者予生活方式及药物干预,10年间对各项临床指标进行随访调查。结果:60例T2DM患者先后服用降糖药治疗者>37.3%;病情重或慢性并发症多者,应用胰岛素替代疗法或与口服降糖药联用或先后阶段性应用,约占56.9%;病情较轻仅以饮食和体育锻炼治疗者占5.9%。血糖、血压控制较理想,血脂、尿白蛋白排泄率需加强控制。并发症中急性者少,慢性并发症增多。10年病死率为10.5%(6/57),主要死亡因素依次为心脑血管病、慢性肾功能不全、多脏器功能衰竭、恶性肿瘤等。结论:DM可防可治,应做到尽早发现、综合强化治疗,进一步加强DM三级预防工作。
OBJECTIVE: To carry out the second epidemiological survey of diabetes mellitus (DM) in Bengbu in 1995. During the 10 years, the tertiary prevention and control network of DM was expanded to raise the level of prevention and treatment. Methods: To guide the survey of 60 T2DM patients among 2282 people in 1995 to make life-style and drug intervention, and to follow up the clinical indexes in 10 years. Results: Sixty patients with T2DM took> 37.3% of the patients who took hypoglycemic agents one after the other. Patients with severe or chronic complications, combined with insulin replacement therapy or with oral hypoglycemic agents or with sequential application accounted for 56.9% Lighter diet and physical activity accounted for only 5.9%. Blood sugar, blood pressure control is more ideal, blood lipids, urinary albumin excretion rate needs to be strengthened control. Acute complications less, increased chronic complications. The 10-year case-fatality rate was 10.5% (6/57). The main causes of death were cardiovascular and cerebrovascular diseases, chronic renal insufficiency, multiple organ failure and malignant tumors. Conclusion: DM is preventable and curable, and should be detected as soon as possible. Comprehensive treatment should be strengthened to further strengthen the prevention of DM.