论文部分内容阅读
目的:探讨口溃宁颗粒的抗炎、镇痛作用。方法:采用小鼠腹腔毛细血管通透性及二甲苯致小鼠耳肿胀试验探讨抗炎作用,采用冰醋酸扭体法和福尔马林致痛试验研究镇痛作用。结果:口溃宁颗粒可明显抑制毛细血管通透性增加、减轻小鼠耳廓肿胀度,减少小鼠扭体反应次数及福尔马林致痛试验的第二时相的疼痛强度。结论:口溃宁颗粒具有较好的镇痛、抗炎作用。
Objective: To investigate the anti-inflammatory and analgesic effects of Kuikui Ning Granule. Methods: The anti-inflammatory effects of peritoneal capillary permeability and xylene-induced mouse ear swelling were investigated. The analgesic effects were studied by using acetic acid writhing method and formalin-induced pain test. Results: Koukui-ning granule can obviously inhibit the increase of capillary permeability, reduce the auricle swelling of mice and reduce the number of writhing reaction and the second-phase pain intensity of formalin test. Conclusion: Koukui-ning granules have good analgesic and anti-inflammatory effects.