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作者在过去八年中,在其工作的医学中心的儿科,见到了7例儿童发生骨髓衰竭,他们无一例接触过其它已知的血液毒毒物,如化疗剂、有机氯农药、苯、γ-射线等。但在发病前曾接触过DDVP、马拉硫磷有机磷农药和残杀威氨基甲酸酯农药,有一例于小屋内吸入浓杀虫剂烟雾达2分钟,其他的则在用杀虫剂烟熏的家中停留了二天。有6例发生再生障碍性贫血,1例为急性成淋巴细胞性白血病。所有病例均有中度至重度白细胞降低。检查的6例中有5例胎儿血红蛋白(HbF)增高。HbF增高并有再障的例7,在一年半前确知其HbF为正常(0.5%)。
In the past eight years, the author saw pediatric bone marrow failure in seven children at a pediatric center where she worked, and none of them had been exposed to other known hematotoxic agents such as chemotherapeutic agents, organochlorine pesticides, benzene, gamma- Ray and so on. However, DDVP, malathion organophosphorus pesticide and carbamate carbamate pesticide were exposed before the onset of disease. One case inhaled insecticide smoke for up to 2 minutes in the cabin while the others were sprayed with insecticide Stayed in the house for two days. Aplastic anemia occurred in 6 cases and acute lymphoblastic leukemia in 1 case. All cases were moderate to severe leukopenia. Five of the 6 examined cases had an increase in fetal hemoglobin (HbF). HbF increased with aplastic anemia in Example 7, a year and a half ago to make sure its HbF is normal (0.5%).