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目的了解患者Rh血型系统RhC、RhD及RhE抗原分布情况,旨在为临床安全用血提供量化资料。方法采用自动血型分析仪对31 752例住院患者及3 000名健康献血者进行RhC、RhD及RhE检测。结果 31 752例住院患者RhC、RhD、及RhE抗原阴性率分别为6.26%、0.30%及51.24%,三者在健康献血者中的阴性率分别为6.77%、0.33%及69.03%;组间比较,差异均无统计学意义(均P>0.05)。结论住院患者Rh血型系统RhE、RhC抗原阴性表达率较高,应同RhD一样引起人们的重视;患者输血治疗前进行RhC、RhD及RhE等血型检测,对于降低输血风险,保障输血安全具有重要临床意义。
Objective To understand the distribution of RhC, RhD and RhE antigens in patients with Rh blood system, and to provide quantitative data for the clinical use of safe blood. Methods Automatic blood type analyzer was used to detect RhC, RhD and RhE in 31 752 inpatients and 3 000 healthy blood donors. Results The negative rates of RhC, RhD and RhE antigens in 31 752 inpatients were 6.26%, 0.30% and 51.24%, respectively. The negative rates of RhC, RhD and anti-RhE antigen in healthy donors were 6.77%, 0.33% and 69.03% , There was no significant difference (all P> 0.05). Conclusions Rh Rh Rh and RhC antigens are highly negative in hospitalized patients, which should be treated as the same as that of RhD. RhC, RhD and RhE tests before transfusion are important for reducing blood transfusion and ensuring blood transfusion safety significance.