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目的:分析慢性鼻-鼻窦炎患者外周血白细胞计数和嗜酸性粒细胞(Eos)比例与鼻窦CT评分的相关性。方法:抽取2020年5月至2021年5月在郑州大学附属郑州中心医院治疗的200例慢性鼻-鼻窦炎患者，设为研究组，另抽取同期在医院体检的200例健康人群为参照组，给予研究组及参照组CT检查及血常规检测，根据Lund-Mackay评分标准对患者进行鼻窦CT评分，记录并比较两组外周血白细胞计数、Eos比例，鼻窦CT中嗅裂、筛窦、上颌窦评分及双侧筛窦总分/双侧上颌窦总分(E/M)，鼻窦CT总评分，分析慢性鼻-鼻窦炎患者外周血白细胞计数、Eos比例与鼻窦CT中嗅裂、筛窦、上颌窦评分，E/M，鼻窦CT总评分的相关性，分析各年龄段慢性鼻-鼻窦炎患者外周血白细胞计数、Eos比例与鼻窦CT总评分的相关性。结果:研究组外周血白细胞计数、Eos比例，嗅裂、筛窦、上颌窦评分，E/M，鼻窦CT总评分均高于参照组(n P均<0.05)。外周血Eos比例与筛窦评分(n r＝0.138，n P＝0.046)、上颌窦评分(n r＝-0.124，n P＝0.041)、E/M(n r＝0.135，n P＝0.045)、鼻窦CT总评分(n r＝0.132，n P＝0.045)有显著相关性，与嗅裂评分(n r＝0.122，n P＝0.052)无相关性，外周血白细胞计数与嗅裂评分(n r＝0.152，n P＝0.023)、筛窦评分(n r＝0.158，n P＝0.017)、上颌窦评分(n r＝-0.134，n P＝0.045)、E/M(n r＝0.285，n P<0.05)、鼻窦CT总评分(n r＝0.162，n P＝0.005)有显著相关性，不同年龄段鼻-鼻窦炎患者外周血白细胞计数、Eos比例与鼻窦CT总评分存在相关性(n P<0.05)。n 结论:慢性鼻-鼻窦炎患者外周血白细胞计数和Eos比例与鼻窦CT评分存在相关性，不同年龄段慢性鼻-鼻窦炎患者外周血白细胞计数、Eos比例与鼻窦CT总评分存在相关性，可根据患者临床症状及其他检查给予患者病情评估，为慢性鼻-鼻窦炎的治疗提供参考。“,”Objective:To analyze the correlation of white blood cell (WBC) count and eosinophils (Eos) ratio with sinus CT score in patients with chronic nasosinusitis.Methods:A total of 200 patients with chronic nasosinusitis treated in Zhengzhou Central Hospital Affiliated to Zhengzhou University from May 2020 to May 2021 were selected as the study group, and 200 healthy people who received physical examination in the same hospital at the same time were selected as the reference group. The study group and the reference group were given CT examinations and routine blood tests. According to Lund-Mackay scoring standard, the patients were scored by nasal sinus CT. WBC count and Eos ratio, scores of olfactory fissure, ethmoid sinus and maxillary sinus, total score of bilateral ethmoid sinus/total score of bilateral maxillary sinus (E/M) and total score of nasal sinus CT were recorded and compared between the two groups. The correlations of WBC count and Eos ratio of patients with chronic rhinosinusitis with the scores of olfactory fissure, ethmoid sinus and maxillary sinus, E/M and total CT score of nasal sinus were analyzed. The correlations of WBC count, Eos ratio and total CT score of chronic rhinosinusitis patients at all ages were analyzed.Results:The WBC count, Eos ratio, scores of olfactory fissure, ethmoid sinus and maxillary sinus, E/M and total CT scores of paranasal sinus in the study group were higher than those in the reference group (all n P<0.05). The proportion of Eos was significantly correlated with ethmoid sinus score (n r=0.138, n P=0.046), maxillary sinus score (n r=-0.124, n P=0.041), E/M (n r=0.135, n P=0.045) and total CT score of nasal sinus (n r=0.132, n P=0.045), but not with olfactory fissure (n r=0.122, n P=0.052); WBC count was significantly correlated with olfactory fissure (n r=0.152, n P=0.023), ethmoid sinus score (n r=0.158, n P=0.017), maxillary sinus score (n r=-0.134, n P=0.045), E/M (n r=0.285, n P<0.05) and total CT score of nasal sinus (n r=0.162, n P=0.005); the WBC count and Eos ratio in patients with nasosinusitis of different ages were correlated with the total CT score of nasal sinuses (n P<0.05).n Conclusions:WBC count and Eos ratio in patients with chronic nasosinusitis are correlated with sinus CT score. There are correlations between WBC count, Eos ratio and CT score of paranasal sinus in patients with chronic nasosinusitis of different ages. The examination gives the patient, based on the clinical symptoms and other factors of the patients, to provides a reference for the treatment of chronic nasosinusitis.