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端粒酶(Telomersae)、凋亡(Apoptosis)及凋亡相关基因与肿瘤的关系,是近年来肿瘤研究领域的热点,有研究表明,在大多数肿瘤、尤其是恶性肿瘤组织中,都有端粒酶阳性的高表达,而凋亡则受到抑制。本文拟对端粒酶、凋亡相关基因bcl-2在肿瘤中的作用及二者关系的最新进展予以介绍和总结。 1 端粒与端粒酶端粒(Telomere)是存在于染色体末端一段特殊富GDNA重复片段(TTAGGG),具有维持染色体正常功能、防止
The relationship between Telomeresae, Apoptosis and apoptosis-related genes and tumors has been a hot topic in the field of tumor research in recent years. Studies have shown that in most tumors, especially malignant tumors, there are end points. Granzyme positive expression is high and apoptosis is inhibited. This article is intended to introduce and summarize the latest advances in the role of telomerase, apoptosis-related gene bcl-2 in tumors and their relationship. Telomere and telomerase Telomere is a special GDNA-repetitive segment (TTAGGG) present at the end of the chromosome, which maintains the normal function of the chromosome and prevents it.