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一般认为人类角膜内皮再生能力极低,损伤后只能依靠周围细胞移行、延展而愈合。然而作者遇到2例因在白内障手术中误用0.25%醋酸(pH3)冲洗前房引起角膜水肿、混浊的病例,却在1～30天内重新恢复透明。为明确机制,作者选与人类角膜内皮再生能力相仿的猫作同样试验,以了解醋酸对角膜内皮的作用及角膜重新透明的原因。实验选用5只成年猫预先测量角膜厚度及内皮镜检以资对照。按双盲法设计,一眼用0.25%醋酸,另眼用等渗盐水。各冲洗前房2分钟后均
Generally believed that human corneal endothelial regeneration is very low, the damage can only rely on the surrounding cell migration, extension and healing. However, the authors encountered two cases of corneal edema and opacity caused by the misuse of 0.25% acetic acid (pH3) in cataract surgery, but returned to transparency within 1 to 30 days. In order to clarify the mechanism, the authors selected the same kind of cats with human corneal endothelial regeneration similar to the experiment to understand the role of acetic acid on the corneal endothelium and corneal re-transparent reasons. Five adult cats were selected for pre-measurement of corneal thickness and endoscopic examination for comparison. Double-blind design, one with 0.25% acetic acid, the other with isotonic saline. After washing the anterior chamber after 2 minutes are