Mechanism of activation of mouse liver microsomal glutations S—transferase by paracetamol treatment

• 作 者: ZhenY LouYJ
• 机 构: DepartmentofPharmacy,DepartmentofPharmacology＆Toxicology
• 出 处: 中国药理学与毒理学杂志
• 发表日期: 2002年6期
• 关键词: 扑热息痛 甘胱甘肽转移酶 微粒体 肝

Microsomal glutathion S-transferase(mGST) is one of the important detoxifcation enzymes in vivo,its modifying activation by drugs has been paid more attention to in pertinent field recently.This study was to explore the influence of paracetamol(Par) on mG