论文部分内容阅读
全身热疗是继手术、放疗、化疗和免疫生物疗法之后肿瘤治疗的又一手段。研究表明,当全身温度都升高到41.8～42.0℃时,通过热作用可以选择性的杀灭肿瘤细胞,并控制肿瘤细胞的广泛转移。全身热疗能与放化疗产生协同效应,其在肿瘤综合治疗中发挥重要作用。近年来,出现了大量关于全身热疗在恶性肿瘤治疗中应用的研究,尤其在晚期恶性肿瘤或难治性肿瘤治疗方面取得了明显的疗效。其中一些研究已进入了Ⅲ期临床试验。本文就全身热疗的研究进展予以综述。
Whole-body hyperthermia is another means of cancer treatment following surgery, radiotherapy, chemotherapy and immunobiotherapy. Studies have shown that when the whole body temperature are raised to 41.8 ~ 42.0 ℃, the tumor cells can be selectively killed by heat and the extensive metastasis of tumor cells can be controlled. Systemic hyperthermia can have a synergistic effect with radiotherapy and chemotherapy, which plays an important role in the comprehensive treatment of cancer. In recent years, there has been a lot of research on the application of systemic hyperthermia in the treatment of malignant tumors, especially in the treatment of advanced malignancies or refractory tumors. Some of these studies have entered Phase III clinical trials. This article reviews the progress of systemic hyperthermia.