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目的:探讨前列腺滑膜肉瘤的影像学特点、临床病理和诊治方法。方法:对1例原发性前列腺滑膜肉瘤的临床诊治资料进行回顾性分析。该例患者行超声、CT、MRI检查。手术后病理证实(免疫组化)。结果:该患者行前列腺肿瘤根治性切除术。病理:镜下所见异型性细胞片状分布,免疫组化:CK34(+),CD99(+),Ki67(+),MYOD1(+/-),Actin(+),CD117(+),dog-1(+/-),Vimentin(+)。诊断原发性前列腺滑膜肉瘤随访6个月,患者存活。结论:原发性前列腺滑模肉瘤临床罕见,确诊依赖病理及免疫组化检查。应与梭形细胞肿瘤、恶性神经鞘瘤、横纹肌肉瘤、间质肉瘤鉴别。治疗以手术为主,需根据肿瘤分级分期决定手术方案及术后是否需行辅助治疗。
Objective: To investigate the imaging features, clinical pathology and diagnosis and treatment of prostatic synovial sarcoma. Methods: One case of primary prostatic synovial sarcoma was retrospectively analyzed. The patient underwent ultrasound, CT, MRI examination. Postoperative pathology confirmed (immunohistochemistry). Results: The patient underwent radical prostatectomy. Pathology: The distribution of atypical cells was observed by microscope. Immunohistochemistry: CK34 (+), CD99 +, Ki67 +, MYOD1 +/-, Actin + CD117 + -1 (+/-), Vimentin (+). Patients with primary prostate synovial sarcoma were followed up for 6 months. Conclusion: Primary PSSL is clinically rare and confirmed by pathology and immunohistochemistry. Spindle cell tumors should be malignant schwannoma, rhabdomyosarcoma, interstitial sarcoma identification. Surgery-based treatment, according to the tumor staging to determine the surgical plan and postoperative need for adjuvant therapy.