Role of E3 ubiquitin ligases in lung cancer

来源 :世界临床肿瘤学杂志 | 被引量 : 0次 | 上传用户:youlishi
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
E3 ubiquitin ligases are a large family of proteins that catalyze the ubiquitination of many protein substrates for targeted degradation by the 26S proteasome.Therefore,E3 ubiquitin ligases play an essential role in a variety of biological processes inclu
其他文献
作为社会精神文明的重要组成部分,体育文化的建设是新农村建设的重要内容,加强农村体育文化的建设对新农村建设和体育事业的繁荣发展有着重要意义。农村体育是我国体育事业的一
Neuroendocrine neoplasms(NENs)are a group of rare and heterogeneous malignancies,which can develop in various organs.The clinical course of NENs is quite hetero
随着我国经济技术的不断增长, 教育行业也在发生着巨大的变化, 对学科的要求越来越高, 不同学科都在进行教学改革,而初中数学作为新课程背景下改革的重要基本学科, 需要对其
An ever increasing demand for new lead compounds in the pharmaceutical industry has led scientists to search for natural bioactive products.Based on this extens
Glioblastomas are characterized by an aggressive local growth pattern,a marked degree of invasiveness and poor prognosis.Tumor invasiveness is facilitated by th
啦啦操起源于欧洲,以其独特的韵律和适宜的节奏,受到世界各国的欢迎,并在世界范围内得到全面的推广,提升了体育教学的质量。啦啦操在体育教学中的特点是较为突出的,在进行工作安排
Ductal carcinoma in situ(DCIS)is a non-obligate precursor of invasive breast cancer with a variable biological behavior which is difficult to accurately predict
Recently,there has been significant progress in the development of genetically-engineered mouse(GEM)models.By introducing genetic alterations and/or signaling a
古诗词是小学语文中的重要组成部分,对学生了解中国文化具有一定的帮助,对学生文学素养、诗词鉴赏能力以及审美能力的提升,具有重要促进意义。但由于古诗词多意义深远,且语言过于
Pancreatic adenocarcinoma is the fourth leading cause of cancer mortality in the United States in both men and women,with a 5-year survival rate of less than 5%