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作者分析31例纵隔淋巴瘤的并发症。主要并发症是:淋巴细胞白血病(9例)和骨髓浸润(2例);中枢神经系并发症(淋巴瘤性软脑膜炎4例和脊髓压迫症2例);纵隔及其邻近的浸润和转移多例)等。并着重探讨纵隔淋巴瘤并发淋巴瘤白血病或中枢神经系统并发症的有关因素。20岁以下的青少年纵隔淋巴瘤患者,其病例类型为淋巴肉瘤分化不良型或未分化型,经常规的治疗失败;临床症象呈进行性恶化,则很易并发淋巴瘤性白血病;若有上述有关因素,如治疗方案中的药物又不易透过血脑屏障或无预防措施,则易并发淋巴瘤性软脑膜炎;位于纵隔后部的纵隔淋巴瘤,则易引起脊髓压迫症。
The authors analyzed the complications of 31 patients with mediastinal lymphoma. The main complications are: lymphocytic leukemia (9 cases) and bone marrow infiltration (2 cases); central nervous system complications (4 cases of lymphomatous meningitis and 2 cases of spinal cord compression); mediastinal and adjacent infiltration and metastasis Many cases) and so on. And focus on mediastinal lymphoma complicated with lymphoma leukemia or central nervous system complications related factors. Patients with juvenile mediastinal lymphoma under 20 years of age, the type of case of lymphosarcoma poorly differentiated or undifferentiated type, the conventional treatment failed; clinical symptoms were progressive deterioration, it is easy to complicated with lymphoma leukemia; if the above Related factors, such as the treatment of drugs in the program is not easy to cross the blood-brain barrier or no preventive measures, it is easy to complicated with lymphomatous meningitis; located in the posterior mediastinal lymph nodes, it is easy to cause spinal cord compression.