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目的:观察阶段性使用乳酸杆菌防治萎缩性阴道炎的临床疗效。方法:将138例萎缩性阴道炎患者随机分为研究组(70例)和对照组(68例)。对照组予倍美力软膏、甲硝唑栓治疗1个疗程(10天),研究组该疗程同时加用乳酸杆菌治疗,并在3、6、9个月随诊后再阶段性使用乳酸杆菌活菌胶囊1个疗程。治疗结束后观察两组的临床疗效,并于3、6、9、12个月各随诊1次,观察两组复发情况。结果:研究组痊愈率和总有效率分别为68.57%和95.71%,明显高于对照组(P<0.01)。治疗后4次随访复诊,研究组复发率分别为1.43%、11.43%、17.14%、24.29%,对照组复发率分别为32.35%、42.65%、54.41%、67.65%,各期复发率研究组较对照组均显著降低(P<0.01)。结论:乳酸杆菌联合倍美力软膏、甲硝唑栓治疗萎缩性阴道炎具有较高有效性,治疗后采用阶段性定期补充乳酸杆菌可显著降低复发率,值得临床推广。
Objective: To observe the clinical efficacy of phacoemulsification in the treatment of atrophic vaginitis. Methods: 138 cases of atrophic vaginitis were randomly divided into study group (70 cases) and control group (68 cases). The control group was treated with Beomei ointment and metronidazole suppository for one course of treatment (10 days). In the study group, Lactobacillus was also added during the course of treatment. After lasted for 3, 6 and 9 months, lactobacilli Live bacteria capsules 1 course of treatment. After the treatment, the clinical curative effect of the two groups was observed. The patients were followed up once every 3, 6, 9 and 12 months to observe the recurrence of the two groups. Results: The cure rate and total effective rate in the study group were 68.57% and 95.71%, respectively, which were significantly higher than those in the control group (P <0.01). The recurrence rates of the study group were 1.43%, 11.43%, 17.14% and 24.29%, respectively. The recurrence rates in the control group were 32.35%, 42.65%, 54.41% and 67.65% The control group were significantly lower (P <0.01). CONCLUSION: Lactobacillus combined with Beimei Li ointment and metronidazole suppository have a higher efficacy in treating atrophic vaginitis. Periodic supplementation with lactobacilli can significantly reduce the recurrence rate after treatment, which is worthy of clinical promotion.