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目的观察中药复方对小鼠学习记忆障碍的影响。方法以东莨菪碱３ｍｇ／ｋｇ腹腔注射复制小鼠学习记忆障碍模型，并以脑复康０．５ｇ／ｋｇ灌胃作为对照，观察了改良三甲散１ｇ／ｋｇ、２ｇ／ｋｇ灌胃对实验动物学习记忆能力的影响。结果改良三甲散能够提高东莨菪碱所诱发的学习记忆障碍小鼠电迷宫测试成绩，拮抗实验动物脑胆碱酯酶活性的升高。结论改良三甲散具有一定的益智抗痴呆作用
Objective To observe the effect of Chinese herbal compound on learning and memory impairment in mice. Methods The scopolamine 3mg/kg intraperitoneal injection was used to replicate the model of learning and memory impairment in mice. The rats were treated with Naofukang 0.5g/kg gavage. The effects of modified Sanjiasan 1g/kg and 2g/kg gavage on the learning and memory of experimental animals were observed. The impact of capacity. RESULTS: Modified Sanjia San could improve the performance of scopolamine-induced learning-memory impairment mice in the electric maze test and antagonize the increase of brain cholinesterase activity in experimental animals. Conclusion Modified Sanjia San has certain anti-dementia effect