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正常人应用生长抑素250μg/hr可减少内脏血流,但对肝硬化患者的肝静脉楔入压和内脏血流则无影响。然而,亦有人认为生长抑素对食管静脉曲张出血有治疗效果。为进一步阐明生长抑素对胃肠道粘膜血供的影响,作者采用中性红胃廓清法检测12名正常人和12例肝硬化患者在滴注生长抑素时的粘膜血流。方法:检测前晚禁食。在X线透视下将双腔胃管末端插至胃窦部。用机械泵连续抽吸胃液,每15分钟收集标本。在第1小时,每15分钟抽血,以后每30分钟抽血,共4小时。实验开始时,静脉注入250μg/kg中
Normal use of somatostatin 250μg / hr can reduce visceral blood flow, but hepatic cirrhosis in patients with hepatic vein wedge pressure and visceral blood flow was no effect. However, some people think that somatostatin bleeding on esophageal varices have a therapeutic effect. To further elucidate the effect of somatostatin on gastrointestinal mucosal blood supply, the authors used a neutral red gastric clearance method to detect 12 normal and 12 patients with cirrhosis of the mucosal blood flow in the infusion of somatostatin. Method: fasting before the test. Insert the end of the double-lumen tube into the antrum under fluoroscopy. The gastric juice was aspirated continuously using a mechanical pump and the specimens were collected every 15 minutes. In the first hour, every 15 minutes blood, every 30 minutes after the blood, a total of 4 hours. At the start of the experiment, 250 [mu] g / kg was intravenously injected