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目的： 观察不同声强的８ Ｈｚ 次声较长时间作用大鼠后，脑心肝肺的 Ｇ Ｓ Ｈ Ｐ Ｘ， Ｓ Ｏ Ｄ活性及 Ｍ Ｄ Ａ 含量的变化以探讨次声作用对组织细胞的影响． 方法：用 ８ Ｈｚ ９０ ｄ Ｂ，１２０ｄ Ｂ 次声作用，每日 ２ ｈ，１４ ｄ 后观察大鼠脑肝心肺组织中 Ｇ Ｓ Ｈ Ｐ Ｘ 活性， Ｓ Ｏ Ｄ 活性及 Ｍ Ｄ Ａ 含量的变化． 结果：大鼠脑肝肺组织中 Ｇ Ｓ Ｈ Ｐ Ｘ活性较对照组均有显著降低（ Ｐ＜ ０．０５， Ｐ＜ ０．０１）． 而心肌组织中 Ｇ Ｓ Ｈ Ｐ Ｘ 活性变化不明显． 大鼠脑肺组织中 Ｓ Ｏ Ｄ 活性及 Ｍ Ｄ Ａ 含量较对照组显著增高（ Ｐ＜００５， Ｐ＜ ０．０１）． 肝及心肌组织中 Ｓ Ｏ Ｄ活性和 Ｍ Ｄ Ａ 含量变化不明显． 结论：次声作用后，大鼠脑肝肺组织活性氧自由基生成增多，从而造成组织细胞的损害．
OBJECTIVE: To observe the changes of G S HP X, S D activity and M D A content in brain, heart, lung and lung of rats with different long-term infrasound with different sound intensities, in order to investigate the effect of infrasound on tissue cells influences. Methods: The changes of G S H-P X activity, SOD activity and M D A content in brain, heart, liver and lung were observed at 2 h, 14 h and 8 d after 90 d B and 120 d B infrasound respectively. . Results: The activity of G S H-P X in the brain, liver and lung tissue of rats was significantly lower than that of the control group (P <0.05, P <0.01). However, the activity of G S H-P X in myocardium did not change significantly. S O D activity and MDA content in rat brain and lung tissue were significantly higher than those in control group (P <005, P <0.01). S O D activity and M D A content in liver and myocardium did not change significantly. Conclusion: After infrasound, the generation of active oxygen free radicals in the brain, liver and lung tissue of rats increased, resulting in the damage of the tissue cells.