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目的观察晚期日本血吸虫病(晚血)巨脾型患者接受外科脾切除手术治疗后的血常规变化情况,以探讨其脾功能亢进能否得以纠正。方法选取105例晚血脾切除术患者和105例晚血巨脾有手术指征者分别进行血常规检查,对其白细胞、红细胞和血小板数的变化情况进行对比分析。结果接受外科治疗切脾手术者白细胞、红细胞和血小板数分别为5.63±1.82(G/L)、4.17±0.72(T/L)和133±75(G/L);而晚血巨脾有手术指征者其白细胞、红细胞和血小板数分别为3.73±1.45(G/L)、3.70±0.71(T/L)和71±49(G/L);差异有统计学意义(P<0.01)。结论晚血巨脾型患者接受外科脾切除治疗后可以纠正脾功能亢进,提高全血细胞数量,有积极临床意义。
Objective To observe the blood routine changes of patients with splenomegaly of late stage schistosomiasis japonica (late blood) treated with surgical splenectomy to investigate whether their hypersplenism can be corrected. Methods A total of 105 patients with splenectomy and 105 patients with splenomegaly were enrolled in this study. Blood samples were collected and analyzed for changes of white blood cells, erythrocytes and platelets. Results The number of white blood cells, erythrocytes and platelets in the splenectomy patients undergoing surgical treatment were 5.63 ± 1.82 (G / L), 4.17 ± 0.72 (T / L) and 133 ± 75 (G / L) Indications were 3.73 ± 1.45 (G / L), 3.70 ± 0.71 (T / L) and 71 ± 49 (G / L) for leukocytes, erythrocytes and platelets, respectively. The difference was statistically significant (P <0.01). Conclusions The late splenomegaly splenic patients receiving splenectomy can correct hypersplenism and increase the number of whole blood cells, which has a positive clinical significance.