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本文在特异性免疫血清存在下，就嗜中性粒细胞和巨噬细胞对周期型马来丝虫幼虫的细胞毒作用进行了超微结构观察。结果显示，两种效应细胞对虫体都具有强大的杀伤作用。该作用开始于效应细胞伸出伪足包围并粘附于虫体，然后分泌颗粒性物质、释放各种对虫体有毒性作用的酶和其它生物活性成分于虫体表面。由于微丝蚴鞘膜和角皮层的溶解和脱落，导致了虫体内部组织迅速变性坏死。电镜下可见虫体肿胀变形、核溶解和空泡样坏死以及最终崩解剥落成絮状等连续变化。本试验还发现效应细胞伪足插入脱鞘微丝蚴内部的现象，说明微丝蚴脱鞘后更易受到效应细胞的攻击。扫描电镜观察到被效应细胞粘附的感染期幼虫表面出现裂痕。
In this paper, in the presence of specific immune serum, the cytotoxic effects of neutrophils and macrophages on the larvae of the periodic line were observed. The results showed that both effector cells have a powerful killing effect on parasites. This effect begins with the effector cells extending around the pseudopodia and adhering to the worm, then secreting particulate matter, releasing various enzymes and other bioactive components that are toxic to the worm, on the surface of the worm. As microfilariae sheath and cortex dissolved and fall off, resulting in rapid degeneration and necrosis of the internal body of parasites. Electron microscope showed swollen and deformed worms, nucleolysis and vacuole-like necrosis and the final collapse and flaking into flocculation and other continuous changes. This experiment also found that the effector cell pseudopods inserted into the internal microfilariae demyelinating phenomenon, indicating that the microfilariae after being more susceptible to attack by effector cells. Scanning electron microscopy showed that there were cracks in the surface of larvae infected with effector cells.