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本文总结我科从1964年1月到1991年6月诊治244例腮腺癌患者的治疗经验。男性147例,女性97例,30~60岁占62.3%。首发癌192例,其中临床Ⅰ、Ⅱ期占51.6%,Ⅲ、Ⅳ期占48.4%;复发癌52例。全组均采用外科手术治疗,其中101例术后加用放疗,面神经被肿瘤累及切除82例(33.6%)。行颈清扫术或腮腺旁淋巴结切除术182例,全组颈淋巴结转移率为32.4%。5、10年生存率分别为75%和59.4%,死亡111例,死于局部复发占55%。作者认为手术是治疗腮腺癌的主要手段,对临床晚期、病理分化差、手术姑息患者应加用术后放疗,以提高局部控制率;面神经被肿瘤累及应予切除;对颈部淋巴结肿大可疑有转移病例应行治疗性颈清术,对病理分化差患者应行选择性颈清术。病理类型、临床分期、是否复发癌及首次治疗是否彻底是影响预后的主要因素。
This article summarizes our department from January 1964 to June 1991 treatment of 244 patients with parotid cancer treatment experience. There were 147 males and 97 females, accounting for 62.3% of those aged 30-60 years. 192 cases of primary cancer, of which clinical stage Ⅰ, Ⅱ accounted for 51.6%, Ⅲ, Ⅳ accounted for 48.4%; recurrent cancer in 52 cases. Surgical treatment was used in all the groups, of which 101 cases were treated with radiotherapy and 82 cases (33.6%) were involved in excision of the facial nerve. 182 cases underwent neck dissection or parotid lymphadenectomy. The rate of cervical lymph node metastasis in the whole group was 32.4%. The 5-year and 10-year survival rates were 75% and 59.4% respectively, 111 died and 55% died of local recurrence. The authors believe that surgery is the main means of treatment of parotid gland cancer, late clinical, poor pathological differentiation, surgical palliative patients should be combined with postoperative radiotherapy to improve the local control rate; facial nerve involvement of the tumor should be resected; neck lymph node enlargement suspicious There are cases of metastasis should be treated neck dissection, poor pathological differentiation should be performed in patients with selective neck dissection. Pathological type, clinical stage, whether the recurrence of cancer and whether the first treatment is the main factor affecting the prognosis.