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白血病细胞相关抑制物(LAI)对正常粒-巨噬系祖细胞(CFU-GM)生长有抑制作用,国内外近年已有较多报道。在体外CFU-GM培养中加入白血病细胞条件培养液,正常CFU-GM的生长受明显抑制,而LAI对正常红系造血的影响报道不多。我们以体外红系祖
Leukemia-related inhibitor (LAI) has an inhibitory effect on the growth of normal granulocyte-macrophage-derived progenitor cells (CFU-GM), and more reports have been reported in recent years. The addition of leukemic cell conditioned medium to CFU-GM in vitro significantly inhibited the growth of normal CFU-GM, while the effect of LAI on normal erythrocytic hematopoiesis was poorly reported. We in vitro erythroid ancestor