新生儿窒息后肾损伤的基础研究与早期诊治

• 作 者: 魏克伦
• 机 构: 中国医科大学第二临床学院 110003
• 出 处: 实用儿科临床杂志
• 发表日期: 2002年S1期
• 关键词: 新生儿窒息 肾损伤 基础研究 窒息新生儿 细胞增殖分化 肾动脉血流 肾小管损害 肾功能 急性肾功能衰竭 围生期缺氧

新生儿窒息是新生儿死亡和伤残的主要病因之一。本病致死致残的主要原因是窒息缺氧造成多脏器 (心、脑、肾等 )损伤。Ｐｅｒｌｍａｎ等报道 ,窒息新生儿约 70 %合并不同程度的脏器损伤 ,其中肾损伤的发生率最高 ,为 5 7%。现有研究表明 ,窒息当时对肾脏的损伤可能并不严重 ,而

Neonatal asphyxia is one of the leading causes of neonatal death and disability. The main cause of death and disability caused by this disease is asphyxiation and hypoxia caused by multiple organs (heart, brain, kidney, etc.) damage. Perlman et al reported that about 70% of neonatal asphyxia combined with varying degrees of organ damage, of which the highest incidence of renal injury was 57%. Existing research shows that the asphyxia of kidney damage may not be serious at the time