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作者对67例不同临床状态的糖尿病肾病患者血、尿糖及血压控制情况与24小时尿蛋白排泄关系进行了观察。微量白蛋白尿及血压正常患者,无论血、尿糖严格控制或一般控制,尿白蛋白排泄量均明显下降;高血压患者血、尿糖严格控制者,尿白蛋白排泄量下降,而一般控制者则不明显。临床白蛋白尿患者,控制血压,尿蛋白及总蛋白排泄下降率非常显著高于控制血、尿糖的下降率,但都不能降至正常。眼底微血管病变阴性患者,严格控制血糖在正常范围,不仅尿白蛋白排量下降,而且50％左右患者可逆转为正常。结果提示早期检出高危患者对治疗和预后均有重要意义。
The author of 67 cases of different clinical diabetic nephropathy in patients with blood, urine glucose and blood pressure control and 24-hour urinary protein excretion was observed. Microalbuminuria and normotensive patients, regardless of strict control of blood or urine glucose or general control, urinary albumin excretion were significantly decreased; hypertensive patients with strict control of blood and urine, urinary albumin excretion decreased, while the general control Who is not obvious. Patients with clinical albuminuria, blood pressure, urinary protein and total protein excretion rate was significantly higher than the control of blood, urine sugar decreased rate, but can not be reduced to normal. Fundus patients with negative microvascular lesions, strict control of blood glucose in the normal range, not only decreased urinary albumin output, and about 50% of patients can be reversed to normal. The results suggest that early detection of high-risk patients are of great significance for the treatment and prognosis.