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目的探讨实施家庭无创通气治疗慢性阻塞性肺疾病(COPD)合并慢性呼吸衰竭64例的临床观察。方法64例慢性阻塞性肺疾病(COPD)合并慢性呼吸衰竭患者分成两组,治疗组给予长期家庭无创正压通气(LTDNPPV)及常规治疗,对照组仅给予常规治疗。两组COPD合并慢性呼吸衰竭的患者疾病程度均符合应用LTDNPPV的适应证和禁忌证[1]。观察比较2年内住院次数、住院时间、血气指标。结果与对照组比较,治疗组治疗后上述多项指标均有明显改善,两组比较具有统计学意义(P<0.05)。结论对有适应LTDNPPV治疗的慢性阻塞性肺疾病(COPD)合并慢性呼吸衰竭患者采取长期家庭无创通气治疗有利于改善病情及防止急性发作。
Objective To investigate the clinical observation of 64 cases of chronic obstructive pulmonary disease (COPD) complicated with chronic respiratory failure by noninvasive ventilation in family. Methods Sixty-four patients with chronic obstructive pulmonary disease (COPD) and chronic respiratory failure were divided into two groups. The patients in the treatment group were given long-term noninvasive positive pressure ventilation (LTDNPPV) and conventional therapy. The control group was given conventional therapy only. Two groups of COPD patients with chronic respiratory failure were in line with the application of LTDNPPV indications and contraindications [1]. Observed and compared the number of hospitalizations within 2 years, hospital stay, blood gas indicators. Results Compared with the control group, the above indexes of the treatment group were significantly improved after treatment, with statistical significance (P <0.05). Conclusion Long-term home-based noninvasive ventilation in patients with chronic obstructive pulmonary disease (COPD) and chronic respiratory failure who have been treated with LTDNPPV is beneficial to improve the condition and prevent acute attacks.