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目的探讨超声造影在肿瘤射频消融治疗(RFA)中的价值。方法选择2012年1月—2013年9月青岛市中心医院收治的53例原发性肝癌患者为观察组,2011年1月—2012年8月收治的48例原发性肝癌患者为对照组,观察组在超声造影指导下,对照组在普通超声引导下行RFA术。结果观察组53例中,表现为动脉期高增强的比例超声造影为81.13%,增强CT/MRI为77.36%(P>0.05)。术后1个月,病灶稳定/完全灭活率观察组(83.02%)高于对照组(60.38%)(P<0.05);肿瘤原位复发率观察组(7.55%)低于对照组(20.75%)(P<0.05)。随访3~12个月,观察组无疾病进展的比例为73.58%,对照组为49.06%(P<0.05)。结论超声造影术中显影良好,不仅指导RFA手术,还可减少肿瘤局部存活率,减少并发症。
Objective To investigate the value of contrast-enhanced ultrasound in tumor radiofrequency ablation (RFA). Methods Fifty-three patients with primary liver cancer admitted to Qingdao Central Hospital from January 2012 to September 2013 were selected as the observation group and 48 patients with primary liver cancer admitted from January 2011 to August 2012 as the control group. Under the guidance of contrast-enhanced ultrasound, the control group underwent RFA under the guidance of general ultrasound. Results In the observation group of 53 cases, the rate of enhanced arterial phase ultrasonography was 81.13% and enhanced CT / MRI was 77.36% (P> 0.05). At 1 month after operation, the stable / complete inactivation rate of the observation group (83.02%) was significantly higher than that of the control group (60.38%) (P <0.05); the in situ recurrence rate of the observation group (7.55%) was lower than that of the control group %) (P <0.05). During follow-up of 3 to 12 months, the rate of disease-free progress in the observation group was 73.58% and in the control group was 49.06% (P <0.05). Conclusions Ultrasound imaging is well developed, not only guide the RFA surgery, but also reduce the local tumor survival rate and reduce complications.