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过敏性紫癜(HSP)是全身性以坏死性小血管炎为主要病理改变的疾病。由此引起的肾脏损害称为过敏性紫癜肾炎(HSPN),简称紫癜性肾炎。本病多见于儿童及青少年,也是小儿时期继发性肾小球病中最常见的[1]。尽管大部分患者预后比较好,但有少部分患者迁延难愈,少数患者可以发展为慢性肾衰。山东大学齐鲁儿童医院2012年1月~2013年10月治疗168例,现将其临床与病理分析如下。1资料与方法1.1一般资料168例患儿,男108例,女60例,年龄6~11岁。所有病例均符合中华医学会儿科学分会肾脏病学组制定的紫癜性肾炎诊断标准,指HSP病程中(多数在6个月内),
Henoch-Schonlein purpura (HSP) is a systemic disease that is mainly pathologically altered with necrotizing vasculitis. The resulting kidney damage known as Henoch-Schonlein purpura nephritis (HSPN), referred to as purpura nephritis. The disease more common in children and adolescents, but also the most common secondary childhood glomerular disease [1]. Although most patients with better prognosis, but a small number of patients with persistent refractory, a small number of patients can develop chronic renal failure. Qilu Children’s Hospital of Shandong University from January 2012 to October 2013 treatment of 168 cases, now its clinical and pathological analysis is as follows. 1 Materials and Methods 1.1 General Information 168 cases of children, 108 males and 60 females, aged 6 to 11 years. All cases were in line with the Chinese Medical Association of Pediatrics nephrology developed the diagnostic criteria for purpura nephritis, HSP refers to the course of the disease (mostly within 6 months)