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例1,女,47岁。因尿频、尿急1天就诊。门诊诊断为尿路感染,给服头孢氨苄胶囊(南京第三制药厂出品,批号为920410)0.375g/次,3次/日,当晚(服药后10小时)患者出现流清涕、打喷嚏,翌晨感觉胸闷、声音嘶哑再次就医。体检:BP17/11kPa,咽部轻度充血,声带水肿,两肺呼吸音粗,心率80次/分,律齐。患者既往有青霉素及磺胺类药物过敏史,拟诊为药物过敏,嘱停服头孢氨苄,给予扑尔敏口服及对症处理,次日患者流清涕、胸闷症状好转,声音嘶哑减轻,第三天上述症状消失。例2,女,34岁。因乳腺炎就诊。因患者青霉素皮试阳性而改用头孢氨苄胶囊(南京第三制药厂出品,批号为920127)。患者服药第二次后(总药量0.75g)
Example 1, female, 47 years old. Urine frequency, urinary urgency treatment. Outpatient diagnosis of urinary tract infection, giving service to cephalexin capsules (Nanjing Pharmaceutical Factory No. 3, lot number 920410) 0.375g / time, 3 times / day, night (10 hours after taking the drug) patients with runny nose, sneezing, Chest tightness felt the next morning, hoarse voice to seek medical treatment again. Physical examination: BP17 / 11kPa, pharyngeal mild congestion, vocal cord edema, coarse breath sounds of both lungs, heart rate 80 beats / min, law Qi. Patients with past history of penicillin and sulfa allergy, to be diagnosed as drug allergy, asked to stop taking cephalexin, give chlorpheniramine oral and symptomatic treatment, the next day patients runny nose, chest tightness symptoms improved, hoarseness reduce the sound, the third day The above symptoms disappear. Example 2, female, 34 years old. Because of mastitis treatment. Due to patients with penicillin skin test and switch to cephalexin capsules (Nanjing Pharmaceutical Factory No. 3, lot number 920127). After taking the second patient (total dose 0.75g)