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大鼠预置心导管 ,3 0 %Ⅲ度烫伤后静脉复苏 ,观察多巴胺 [3 μg/(kg·min) ]持续给药后大鼠的血清乳酸、一氧化氮 (NO)水平的变化。结果显示 ,与对照组相比 ,多巴胺治疗能显著降低严重烫伤大鼠血清中的乳酸、NO水平 ,以伤后 3～ 12h明显。研究表明 ,多巴胺可降低严重烫伤大鼠休克期血清乳酸、NO水平。
The rats were pre-set with a cardiac catheter and the vein was resuscitated after 3 0% Ⅲ degree scald to observe the changes of serum lactate and nitric oxide (NO) in rats after continuous administration of dopamine [3 μg / (kg · min)]. The results showed that compared with the control group, dopamine treatment could significantly reduce the level of lactic acid and NO in the serum of severely scalded rats, which was obvious at 3 ~ 12 h after injury. Studies have shown that dopamine can reduce the Serum lactic acid, NO levels in severely scalded rats during shock.