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目的 探讨某些活动期风湿病患者左心室功能改变、心肌损害以及放射性核素显像检测风湿病患者心脏损害的临床应用价值。方法 用放射性核素显像平衡法门电路心血池扫描及心肌断层显像测定20 例正常人和20 例系统性红斑狼疮(SLE) ,6 例多发性肌炎(PM),6 例结节性动脉炎(PAN),5 例风湿热患者左心室收缩和舒张功能改变、心肌损害情况。结果 活动期风湿病病人的左室射血分数(LVEF),高峰射血率(PER),高峰充盈率(PFR) ,左室相角程(SH) 均较正常对照有显著差异( P< 0-01) ,室壁活动异常的阳性率为48-6 % ,心肌显像阳性率为57-7 % 。结论 活动期风湿病患者左心室功能及心肌明显损害,放射性核素显像可客观评价风湿病患者心脏损害,对临床治疗有指导意义。
Objective To investigate the clinical value of left ventricular function, myocardial damage and radionuclide imaging in patients with rheumatic heart disease in some active stage. Methods Twenty patients with normal subjects, 20 patients with systemic lupus erythematosus (SLE), 6 patients with polymyositis (PM) and 6 patients with nodular arteries were examined by means of radionuclide scintillation counter-flow cytometry and myocardial perfusion imaging. Inflammation (PAN), left ventricular systolic and diastolic changes in 5 patients with rheumatic fever and myocardial damage. Results LVEF, PER, PFR and SH in active rheumatism patients were significantly different from those in normal controls (P <0 -01), the positive rate of abnormal wall activity was 48-6%, the positive rate of myocardial imaging was 57-7%. Conclusions Active left ventricular function and myocardial damage in patients with rheumatic diseases, radionuclide imaging can objectively evaluate the heart damage in patients with rheumatic diseases, which is of guiding significance for clinical treatment.