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  5. Alum colloid encapsulated inside β-glucan particles enhance humoral and CTL immune responses of MUC1

Alum colloid encapsulated inside β-glucan particles enhance humoral and CTL immune responses of MUC1

来源 :中国化学快报:英文版 | 被引量 : 0次 | 上传用户：bitlycold
【摘 要】
：
We have developed a MUC1 antigen-based antitumor vaccine loaded on alum colloid encapsulated insideβ-glucan particles(GP-Al).The constructed vaccine induced strong MUC1 antigen specific Ig G antibody titers and enhanced CD8+T cells cytotoxic ef
【作 者】
：
Yonghui Liu Mingjing Li Haomiao Zhu Zhe Jing Xiaona Yin Kun Wang Zhangyong Hong Wei Zhao 
【机 构】
：
StateKeyLaboratoryofMedicinalChemicalBiology,StateKeyLaboratoryofMedicinalChemicalBiology&Tianji
【出 处】
：
中国化学快报:英文版
【发表日期】
：
2021年6期
【关键词】
：
MUC 1 antigen GLYCOPEPTIDE GP-Al Adjuvant Antitumor vaccine 
【基金项目】
：
supported by the National Natural Science Foundation of China(No.22077068),the National Key R&D Program of China(No.2018YFA0507204),the NCC Fund(No.NCC2020FH12),the Natural Science Foundation of T
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We have developed a MUC1 antigen-based antitumor vaccine loaded on alum colloid encapsulated insideβ-glucan particles(GP-Al).The constructed vaccine induced strong MUC1 antigen specific Ig G antibody titers and enhanced CD8+T cells cytotoxic ef
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