论文部分内容阅读
阴沟杆菌与产气杆菌为肠杆菌属的革蓝氏阴性杆菌,是条件致病菌,也是目前医院内感染的常见病原菌.它们对常见的抗生素多耐药.阴沟杆菌化脓性脑膜炎的病情严重,难以救治.头孢噻肟(Cefotaxime,HR756)是一广谱、高效、低毒与耐酶的第三代头孢菌素,对很多革蓝氏阴性杆菌有高度抗菌活性.1985年我们用四川抗菌素工业研究所与东北制药总厂试制的头孢噻肟治疗一例听神经瘤切除术后并发的阴沟杆菌化脓性脑膜炎,迅获治愈.兹将治疗剂量与用法、血与脑脊液中该药浓度监测,连续多次脑脊液培养观察,以及恢复期发热问题的诊治等探讨资料,按顺序分析如下,以供治疗该类化脓性脑膜炎的参考.
Enterobacter cloacae and gas-producing bacilli are Enterobacter gram-negative bacilli, is a conditional pathogenic bacteria, is also a common pathogen in hospital infections. They are more resistant to common antibiotics.Celobacter purpura meningitis in severe condition , Difficult to cure.Cefotaxime (HR756) is a broad-spectrum, high efficiency, low toxicity and enzyme-resistant third generation cephalosporins, a lot of gram-negative bacilli has a high degree of antibacterial activity.In 1985 we use Sichuan antibiotics Industrial Research Institute and Northeast Pharmaceutical Factory trial of cefotaxime for the treatment of a case of acoustic neuroma complicated by Corynebacterium purulent meningitis, was quickly cured. Will treat the dose and usage, blood and cerebrospinal fluid concentrations of the drug monitoring, continuous Multiple cerebrospinal fluid culture observation, as well as the diagnosis and treatment of convalescent fever and other discussion materials, according to the order analysis as follows, for the treatment of such purulent meningitis reference.