The Comparison Study of Renin and Angiotensin A H Levels on Normal Tension Glaucoma Patients and Nor

• 作 者: Hongmin Yun Pei Fu Kexi Ding Qi Yang
• 机 构: Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen 518036, China
• 出 处: 眼科学报
• 发表日期: 2005年3期
• 关键词: normal tension glaucoma renin angiotensin A Ⅱ renin-angiotension system

Purpose: To investigate the levels of renin-angiotension system (RAS) components in normal tension glaucoma patients and normal controls.Methods: Blood samples were obtained from 11 normal tension glaucoma(NTG)patients and 11 age and sex matched controls. The levels of renin and angiotensin A Ⅱ of 11 NTG patients and normal controls were examined by radio-immunity test. Statistical analyses were performed by paired t test.Results :The levels of renin of NTG patients and normal controls are (769.085±183.217) pg/ml/n and (822.035±124.140) pg/ml/n, while the levels of angiotensin A Ⅱ of NTG patients and normal controls are (37.347±10.669)pg/ml and (24.836±10.665)pg/ml respectively. No statistically significant differences were observed between the levels of renin and angiotensin among NTG patients and normal controls.Conclusion:There were not many abnormalities of the levels of circulating rennin and angiotensin A Ⅱ of NTG patients in our study.