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目的研究子宫动脉栓塞术治疗子宫瘢痕妊娠对卵巢功能的影响。方法选择2012年1月至2014年2月来舞阳县人民医院行子宫动脉栓塞术的60例子宫瘢痕妊娠患者作为研究对象,术后随访1年,观察手术前后患者卵泡刺激素(FSH)、血清雌二醇(E2)、黄体生成素(LH)及睾酮(T)等卵巢生殖激素水平,并跟踪观察有生育要求患者的月经和妊娠情况。结果手术前后FSH、E2及LH比较,差异无统计学意义(P>0.05),术后1周和术后1个月T水平较手术前显著下降,差异具有统计学意义(P<0.05),但术后3个月与术后6月T值较手术前差异无统计学意义(P>0.05)。治疗前后32例有生育要求的患者月经周期和经期分别为(30.84±3.71)d和(5.41±2.03)d,对照组分别为(29.58±3.75)d和(4.72±2.15)d,差异无统计学意义(P>0.05),所有患者均在术后4个月内恢复排卵,其中有生育要求的患者术后9个月内共有19例(59.38%)成功妊娠。结论子宫动脉栓塞术治疗子宫瘢痕妊娠对患者术后月经及卵巢功能影响小,具有可逆性,不影响正常月经,术后多数患者可再次妊娠。
Objective To study the effect of uterine artery embolization on ovarian function in uterine scar pregnancy. Methods From January 2012 to February 2014, 60 cases of uterine scar pregnancy undergoing uterine arterial embolization in Wuyang County People’s Hospital were selected as research object. The patients were followed up for 1 year. The levels of follicle stimulating hormone (FSH), serum Estradiol (E2), luteinizing hormone (LH) and testosterone (T), and to observe the menstrual and pregnancy status of patients with reproductive requirements. Results There was no significant difference in FSH, E2 and LH between before and after operation (P> 0.05). The level of T decreased significantly at 1 week and 1 month after operation compared with that before operation (P <0.05) However, there was no significant difference in T value between 3 months after operation and 6 months after operation (P> 0.05). Before and after treatment, 32 patients with reproductive requirements had menstrual cycle and menstrual cycle of (30.84 ± 3.71) days and (5.41 ± 2.03 days), respectively, and (29.58 ± 3.75) days and (4.72 ± 2.15) days in control group (P> 0.05). All patients recovered ovulation within 4 months after operation. Among them, 19 patients (59.38%) had successful pregnancy within 9 months after birth. Conclusion Uterine artery embolization for the treatment of uterine scar pregnancy on postoperative menstrual and ovarian function of a small, reversible, does not affect the normal menstruation, postoperative majority of patients can be pregnant again.