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目的:观察分析终末期肾病血液透析患者心血管疾病的危险因素。方法:选取2017年1月~2017年6月于本院接受血液透析治疗的90例患者作为临床观察对象,患者透析时间均超过6个月,根据收集的患者临床信息,将患者分为无心血管疾病组(n=34)和有心血管疾病组(n=56),对两组患者的年龄、血压、人血白蛋白(ALB)、血红蛋白(HB)、血肌酐(Scr)、甘油三酯(TC)、血钙、血磷、尿酸(UA)、C反应蛋白(CRP)、尿素氮(BUN)、尿素清除指数(Kt/V)等行分析对比,探讨血液透析患者心血管疾病的影响因素。结果:经检测发现,相比于无心血管疾病组,心血管疾病组患者的年龄、血压、透析持续时间、血磷、血肌酐、C反应蛋白、甘油三酯等水平均明显较高;尿素清除指数、血尿酸和血红蛋白明显较低,差异均具有统计学意义(P<0.05)。结论:终末期肾病血液透析患者容易出现心血管疾病等常见并发症,其中患者年纪大、血压高、血红蛋白减少及血磷、血肌酐、C反应蛋白、甘油三酯等水平升高是影响血液透析患者发生心血管疾病的重要影响因素。
Objective: To observe and analyze the risk factors of cardiovascular disease in hemodialysis patients with end stage renal disease. Methods: Totally 90 patients undergoing hemodialysis in our hospital from January 2017 to June 2017 were enrolled in this study. All patients underwent dialysis for more than 6 months. According to the clinical data collected, (N = 34) and patients with cardiovascular disease (n = 56). The age, blood pressure, ALB, HB, Scr and triglyceride TC, serum calcium, phosphorus, uric acid (UA), C-reactive protein (CRP), blood urea nitrogen (BUN) and urea clearance index (Kt / V) were measured to investigate the influencing factors of cardiovascular disease in hemodialysis patients . Results: The levels of serum phosphorus, serum creatinine, C-reactive protein and triglyceride in patients with cardiovascular disease were significantly higher than those without cardiovascular disease. The levels of urea clearance Index, serum uric acid and hemoglobin were significantly lower, the difference was statistically significant (P <0.05). CONCLUSIONS: End-stage renal disease patients with hemodialysis are prone to common complications such as cardiovascular disease. Among them, patients with high age, high blood pressure, decreased hemoglobin and elevated serum phosphorus, serum creatinine, C-reactive protein, and triglyceride are the factors affecting hemodialysis Patients with cardiovascular disease, an important factor.