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目的 :利用 TL C和 HPL C对解热抗炎 号口服液中有效成分大黄素进行定性、定量分析。方法 :用 TL C法对成分大黄素和薄荷进行定性分析 ,以 HPL C法在 ODS- C1 8柱上以甲醇 - 0 .1%高氯酸 (2 0∶ 80 )为流动相测定其含量。结果 :大黄素回收率为 96 .89% (RSD =0 .96 % ) ,检测范围为 0 .0 5～ 0 .8μg/ m L ,r=0 .9995 ,可以作为该制剂的质控方法。结论 :所用定性、定量方法快速简便、灵敏度高、重现行好。
Objective :To qualitatively and quantitatively analyze emodin, the active ingredient in antipyretic and anti-inflammatory oral liquid, using TL C and HPL C. Methods: The emodin and peppermint were qualitatively analyzed by TL C method. The content of emodin and peppermint was determined by HPLC on ODS-C18 column with methanol-0.1% perchloric acid (20:80) as the mobile phase. Results: The recovery rate of emodin was 96.89% (RSD=0.96%). The detection range was 0.5 to 0.8 g/m L, r=0.9995. It could be used as a quality control method for this preparation. Conclusion : The qualitative and quantitative methods used are quick and easy, with high sensitivity and good re-use.