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人类细胞遗传学的发展表明,科学的进展取决于新方法的探讨。淋巴细胞培养技术的应用,标志着临床细胞遗传学的开始。但由于淋巴细胞寿命有限,又由于种种原因不易重新得到病人的血标本,这样,给临床诊断和研究带来一定困难。目前,常规运用一种简单方法,很有成效,此法是通过EB病毒(Epstein-Barr Virus,EBV)有效地转化外周血B淋巴细胞,并由此建立永久
The development of human cytogenetics shows that the progress of science depends on the exploration of new methods. The application of lymphocyte culture technology marks the beginning of clinical cytogenetics. However, due to the limited life span of lymphocytes, and due to various reasons difficult to re-obtain the patient’s blood samples, so that clinical diagnosis and research to bring some difficulties. At present, it is very effective to routinely use a simple method which effectively transforms peripheral blood B lymphocytes by Epstein-Barr Virus (EBV) and thereby establishes a permanent