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1994年～1995年夏秋曾在嘉兴市部分地区流行急性细菌性痢疾,我们用多种抗生素治疗效果不佳,后用环丙沙星治疗,取得满意效果。 1 资料与方法 1.1 一般资料 将本病患儿64例分为:①环丙沙星治疗组:33例,男15例,女18例。年龄:3个月～1岁7例,～3岁13例,～7岁11例,～14岁2例;②诺氟沙星(氟哌酸)+阿米卡星(丁胺卡那霉素)为对照组:31例,男18例,女13例。年龄:7个月～1岁10例,～3岁13例,～7岁17例,～14岁1例。64例中发热62例,呕吐31例,腹泻64例,腹痛42例,抽搐6例。粪常规检查均有红细胞、白细胞,脓细胞+～卅。粪培养:14例有细菌生长,均为福氏志贺菌。药物敏感试验:诺氟沙星、阿米卡星敏感,对复方磺胺甲(口恶心)唑(SMZco)、氨苄西林(氨苄青霉素)耐药。 1.2 治疗方法 治疗组:环丙沙星注射液10mg/(kg·d)～15mg/(kg·d),分2次静脉滴注。对照组:诺氟沙星10mg/(kg·d)～15 mg/(ke·d),分
From 1994 to 1995, summer and autumn had epidemic acute bacillary dysentery in some areas of Jiaxing City. We treated with various antibiotics ineffectively and then treated with ciprofloxacin to obtain satisfactory results. 1 Materials and Methods 1.1 General Information The 64 patients were divided into: ① ciprofloxacin treatment group: 33 cases, 15 males and 18 females. Age: 3 months to 1 year in 7 cases, ~ 3 years in 13 cases, ~ 7 years in 11 cases, ~ 14 years in 2 cases; ② norfloxacin (norfloxacin) + amikacin Su) for the control group: 31 cases, 18 males and 13 females. Age: 7 months to 1 year in 10 cases, ~ 3 years in 13 cases, ~ 7 years in 17 cases, ~ 14 years in 1 case. 64 cases of fever in 62 cases, 31 cases of vomiting, diarrhea in 64 cases, 42 cases of abdominal pain, convulsions in 6 cases. Dung routine examination has red blood cells, white blood cells, pus + ~ 卅. Fecal culture: 14 cases of bacterial growth, are Shigella flexneri. Drug sensitivity test: Norfloxacin, amikacin sensitivity of the compound sulfamethoxazole (SMZco), ampicillin (ampicillin) resistance. 1.2 treatment group: ciprofloxacin injection 10mg / (kg · d) ~ 15mg / (kg · d), divided into 2 intravenous drip. Control group: Norfloxacin 10mg / (kg · d) ~ 15 mg / (ke · d), points