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将二硝基苯（DNP）基团与牛血清白蛋白（BSA）共价结合制成DNP－BSA结合物（比例为3O：1）后，与细胞因子白细胞介素5（IL－5）和IL－6混合溶解于聚DL－丙交酯－乙交酯聚合物（PLG）溶液中，通过油包水溶剂蒸发制成生物降解微粒（MP）。经电镜扫描显示MP的平均直径为1.7μm，基本呈球
DNP-BSA was covalently bound to DNP-BSA conjugate (30: 1 ratio) and then incubated with cytokines interleukin 5 (IL-5) and IL-6 is mixed and dissolved in poly-DL-lactide-glycolide (PLG) solution, and then biodegraded microparticles (MP) are formed by evaporation of the water-in-oil solvent. Electron microscopy showed MP average diameter of 1.7μm, basically spherical