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目的：观察癫痫病人应用卡马西平（ＣＢＺ）治疗前后脑电背景活动的变化情况。方法：对３０例癫痫病人给予单一卡马西平治疗，比较服药前、服药３０天后的脑电活动。结果：服药后总功率和α、β、θ、δ各频段的绝对功率变化不明显，α、β、δ频段相对功率变化也不明显，而θ相对功率较用药前显著增加，其增加值与血ＣＢＺ、ＣＢＺ—Ｅ浓度呈正向线性关系。结论：脑电背景活动不能作为卡马西平治疗有效的一种指标。
Objective: To observe the change of EEG background activity in patients with epilepsy before and after treatment with carbamazepine (CBZ). Methods: 30 cases of epilepsy patients given a single carbamazepine treatment, compared with medication, medication 30 days after the EEG activity. Results: The absolute power changes of total power and α, β, θ, δ bands were not obvious after treatment, and the relative power changes of α, β and δ bands were not obvious, while the relative power of θ increased significantly compared with that before treatment, Blood CBZ, CBZ-E concentration showed a positive linear relationship. Conclusion: The background activity of brain electricity can not be used as an effective indicator of carbamazepine treatment.