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目的:比较泮托拉唑10d序贯疗法与传统10 d三联疗法根除幽门螺杆菌(Hp)的临床效果。方法:60例门诊患者随机分为治疗组与对照组各30例。治疗组给予10 d序贯疗法,对照组给予传统10 d三联疗法。结果:治疗组与对照组的临床有效率分别为96.67%,73.33%;两种方案的Hp根除率分别为93.33%,70.00%,差异均有统计学意义(P<0.05)。结论:泮托拉唑10 d序贯疗法是用于Hp根治的优选方案。
Objective: To compare the clinical efficacy of 10-day sequential therapy with pantoprazole and traditional triple therapy in the treatment of Helicobacter pylori (Hp). Methods: Sixty outpatients were randomly divided into treatment group and control group, 30 cases each. The treatment group was given 10 days sequential therapy, while the control group was given the traditional 10 d triple therapy. Results: The clinical efficacies of the treatment group and the control group were 96.67% and 73.33%, respectively. The Hp eradication rates of the two regimens were 93.33% and 70.00%, respectively, with statistical significance (P <0.05). Conclusions: The sequential therapy of pantoprazole 10 d is the best choice for Hp radical.