双能X射线吸收法在大鼠骨矿测量中的精确度和准确度

• 作 者: 陈金标 秦林林 马海波 张卫 葛崇华 肖艳霞
• 机 构: 临床医学研究所同位素室
• 出 处: 中日友好医院学报
• 发表日期: 1996年03期
• 关键词: 双能 骨密度 大鼠股骨 鼠骨 放射造影术 骨矿密度 骨矿含量 重复测量 仪器测量 变异系数

为了评价ＬｕｎａｒＤＰＸＬ型双能Ｘ射线骨密度仪测定小动物骨矿含量（ＢＭＣ）的精确度和准确度，在体外、体内重复测量大鼠股骨的ＢＭＣ，并将其与灰重比较。结果体外测量的变异系数（ＣＶ％）ＢＭＣ为１１４，骨矿密度（ＢＭＤ）为０９０，体内测量分别为２６７、１４８。ＢＭＣ体外＝１０５６×灰重，ＳＥＥ＝０００４；ＢＭＣ体内＝１０５２×灰重，ＳＥＥ＝００１６，二者ｒ＞０９９（Ｐ＜００１）。说明该型仪器测量小动物骨矿具有很高的准确度和精确度，感兴趣区的确定在其中起重要作用。

In order to evaluate the accuracy and accuracy of Lunar DPXL dual-energy X-ray absorptiometry in determining the bone mineral content (BMC) of small animals, BMCs of rat femurs were repeatedly measured in vitro and in vivo and compared with gray weight. Results The coefficient of variation (CV%) for in vitro measurement of BMC was 1  14, bone mineral density (BMD) was 0  90, and in vivo measurements were 2  67,1  48. BMC in vitro = 1056 × gray weight, SEE = 0004; BMC in vivo = 1052 × gray weight, SEE = 0016, both r> 099 (P <001). Indicating that this type of instrument to measure small animal bone with high accuracy and accuracy, the determination of the region of interest plays an important role.