论文部分内容阅读
目的:了解引起神经系统不良反应的药物及相关因素。方法:收集我院2007～2008年发生的神经系统药品不良反应、事件(ADR/ADE)报告197例,并进行统计、分析。结果:197例ADR/ADE中,>60岁者80例,占40.61%;采用静脉滴注给药者149例,占75.63%;183例属药品不良反应范畴,14例属药品不良事件范畴;引起神经系统不良反应的药物主要为抗菌药物,其次为中药制剂;大部分停药后好转,少数患者给予对症治疗后好转。结论:神经系统ADR涉及药物种类多,表现多样,应引起临床医生的重视。
Objective: To understand the drugs and related factors that cause adverse reactions of the nervous system. Methods: A total of 197 ADR / ADE cases were collected from 2007 to 2008 in our hospital for statistical analysis. Results: In 197 ADR / ADE patients, 80 cases were more than 60 years old (40.61%), 149 cases were intravenous infusion (75.63%), 183 cases were adverse drug reactions and 14 cases were adverse drug events. Drugs that cause adverse reactions to the nervous system are mainly antimicrobial drugs, followed by traditional Chinese medicine preparations; most discontinued after the improvement, a small number of patients treated with symptomatic improvement. Conclusion: Nervous system ADR involves many kinds of drugs and has various manifestations, which should be taken seriously by clinicians.