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目的:观察莫西沙星口服治疗社区获得性肺炎,特别是右中叶肺炎的疗效。方法:将88例社区获得性右中叶肺炎患者随机分为治疗组46例和对照组42例,治疗组以莫西沙星片400mg,p0 qd,10～14d,对照组以左氧氟沙星注射剂500mg加入0.9%氯化钠注射液100ml,ivd qd,10～14d。两组均佐以止咳平喘化痰退热等对症治疗。结果:两组的临床疗效、细菌学检查、不良反应等比较差异无统计学意义(P>0.05),总有效率分别为89.1%和90.5%。结论:莫西沙星片,治疗右中叶肺炎可缩短住院时间,减少不良反应发生,使患者依从性提高,是治疗社区获得性肺炎的有效药物。
Objective: To observe the efficacy of moxifloxacin oral treatment of community-acquired pneumonia, especially right middle lobe pneumonia. Methods: Eighty-eight patients with community acquired right middle lobe pneumonia were randomly divided into treatment group (n = 46) and control group (n = 42). Moxifaxacin 400 mg, p0 qd for 10-14 d and control group were treated with 500 mg levofloxacin injection. Sodium chloride injection 100ml, ivd qd, 10 ~ 14d. Both groups were accompanied by cough, asthma and phlegm fever and other symptomatic treatment. Results: There was no significant difference in clinical curative effect, bacteriological examination and adverse reactions between the two groups (P> 0.05). The total effective rates were 89.1% and 90.5% respectively. Conclusion: Moxifloxacin tablets, the treatment of right middle lobe pneumonia can reduce hospitalization time, reduce adverse reactions, improve patient compliance, is an effective drug for the treatment of community-acquired pneumonia.