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目的了解孕前妇女TORCH感染情况,对筛查出的风疹病毒抗体阴性者,通过注射风疹疫苗,获得主动免疫后再怀孕,对弓形虫抗体阳性,巨细胞病毒,单纯疱疹病毒及其他病毒感染者,转诊到相关医疗单位进行治疗,以减少缺陷儿的出生。方法采用生物芯片技术对20000例孕前妇女的血清进行TORCH病原体IgM检测。结果TORCH-IgM总阳性1784例、阳性率8.92%,单项病原体感染1395例、阳性率6.98%,合并感染(两种以上病原体)389例、阳性率1.95%。总Tox-IgM阳性419例、阳性率2.09%,RuV-IgM阳性825例、阳性率4.13%,CMV-IgM阳性423例、阳性率2.12%,HSV-I-IgM阳性422例、阳性率2.11%,HSV-Ⅱ-IgM阳性233例、阳性率1.17%。结论孕前妇女TORCH检测对预防宫内感染和畸形胎儿出生,提高出生人口素质具有非常重要的意义,建议将TORCH检测作为孕前常规检查项目。
Objective To understand the prevalence of TORCH infection in prenatal women. For rubella virus negative patients who were screened out, rubella vaccine was injected to get pregnant after active immunization, positive for Toxoplasma gondii, cytomegalovirus, herpes simplex virus and other virus infections. Referral to the relevant medical unit for treatment to reduce the birth of defective children. Methods The biopsy technique was used to detect TORCH pathogen IgM in sera of 20,000 pregnant women before pregnancy. Results The total positive TORCH-IgM was 1784, the positive rate was 8.92%. There were 1395 cases with single pathogen infection, the positive rate was 6.98%. There were 389 cases with infection (more than two pathogens), the positive rate was 1.95%. The total positive rate of Tox-IgM was 419, the positive rate was 2.09%. The positive rate of RuV-IgM was 4.13%. The positive rate of CMV-IgM was 423. The positive rate was 2.12%. The positive rate of HSV-IgM was 2.11% , 233 cases of HSV-Ⅱ-IgM positive, the positive rate of 1.17%. Conclusion TORCH testing before pregnancy is very important for preventing intrauterine infection and birth of deformed fetus and improving the quality of birth population. It is suggested that TORCH test should be taken as routine examination before pregnancy.