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目的分析内镜切除治疗无明确转移的胃巨大问质瘤的临床效果和安全性。方法胃巨大间质瘤患者90例,根据治疗方式不同分为内镜治疗组、开腹手术组及腹腔镜手术组,其中内镜组25例,开腹手术组34例,腹腔镜手术组31例。观察3组的术中出血、穿孔发生情况、整块切除率和随访结果,比较3组患者的手术时间、住院时间和住院费用。结果内镜组成功23例,切除率92.0%,平均手术时间(61.37±15.34)分钟,住院时间(5.74±1.44)天,均显著短于开腹手术组[(117.68±29.42)分钟,(12.16±3.04)天]和腹腔镜手术组[(100.26±25.07)分钟,(9.38±2.35)天];平均治疗总费用(22839.26±5709.82)元,显著少于开腹手术组[(31017.62±7754.41)元],差异有统计学意义(P<0.05);3组患者术后随访均未发现严重的并发症,无死亡病例。结论内镜切除治疗无明确转移的胃巨大间质瘤,安全可行,手术时间和住院时间短,治疗费用较少。
Objective To analyze the clinical effect and safety of endoscopic resection in the treatment of giant gastric tumor with no metastasis. Methods Ninety patients with giant gastric stromal tumor were divided into two groups: endoscopic group, laparotomy group and laparoscopic group, including 25 cases of endoscopic group, 34 cases of open surgery group, 31 cases of laparoscopic surgery group example. The intraoperative hemorrhage, perforation, the resection rate and the follow-up results of the three groups were observed. The operation time, hospitalization time and hospitalization cost of the three groups were compared. Results In the endoscopic group, 23 cases were successful, the resection rate was 92.0%, the average operation time was 61.37 ± 15.34 minutes and the hospitalization time was 5.74 ± 1.44 days, which was significantly shorter than that of the open surgery group (117.68 ± 29.42 minutes, The mean total cost of treatment (22839.26 ± 5709.82) yuan was significantly lower than that of the open surgery group [(31017.62 ± 7754.41) ± 3.04) days and laparoscopic surgery group (100.26 ± 25.07 minutes, 9.38 ± 2.35 days) Yuan], the difference was statistically significant (P <0.05); 3 groups of patients were followed up were no serious complications, no deaths. Conclusion Endoscopic resection of gastric giant stromal tumor without clear metastasis is safe and feasible, the operation time and hospitalization time are short, and the treatment cost is less.