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目的:探讨18F-FDG符合线路SPECT在消化系统肿瘤术后复发转移中的临床应用价值。材料和方法:对35例临床怀疑复发转移的消化系统肿瘤术后患者行18F-FDG符合线路SPECT显像,对其显像结果进行分析,计算其诊断的准确率、灵敏度、特异性、阳性预测值、阴性预测值及其95％可信区间,并与B超、CT、MRI的诊断结果相比较。结果:在35例消化系统肿瘤术后患者中,其诊断的准确率、灵敏度、特异性、阳性预测值、阴性预测值分别为91.4％、88.9％、100％、100％、72.7％;其95％可信区间分别为77％-98％、71％-98％、63％-100％、86％-100％、39％-94％。符合线路SPECT的诊断准确率、灵敏度明显高于B超,与CT和MRI的比较尚无显著性差异;95％可信区间分析,结果显示符合线路SPECT高于B超、CT和MRI;18F-FDG符合线路SPECT和B超、CT、MRI联合应用在某些病例的诊断中具有互补性。结论:18F-FDG SPECT/PET显像在消化系统肿瘤术后复发转移的诊断中具有较高的临床应用价值。
Objective: To investigate the clinical value of 18F-FDG coincidence SPECT in recurrence and metastasis of digestive system tumors. MATERIALS AND METHODS: We performed 18F-FDG coincidence SPECT imaging in 35 postoperative patients with suspected tumor recurrence and metastasis. The imaging results were analyzed and the diagnostic accuracy, sensitivity, specificity, positive predictive value Value, negative predictive value and 95% confidence interval, and with B ultrasound, CT, MRI diagnostic results compared. Results: The diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value were 91.4%, 88.9%, 100%, 100% and 72.7% respectively in 35 patients with digestive system tumors. % Confidence intervals were 77% -98%, 71% -98%, 63% -100%, 86% -100%, 39% -94%, respectively. The diagnostic accuracy and sensitivity of the line SPECT were significantly higher than those of the B ultrasound. There was no significant difference compared with the CT and MRI. The 95% confidence interval analysis showed that line SPECT was higher than B-mode, CT and MRI, 18F- FDG coincidence SPECT and B ultrasound, CT, MRI in the diagnosis of some cases have complementary. Conclusion: 18F-FDG SPECT / PET imaging in the diagnosis of digestive system tumor recurrence and metastasis has a high clinical value.