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庆大霉素是广谱抗菌素,临床广泛用于各种严重感染性疾患。但近年来庆大霉素的严重副作用屡有报道,以过敏反应最为常见。我院遇到1例庆大霉素引起重症过敏性紫癜伴发紫癜性肾炎,报告如下,并结合文献加以讨论。患者,男,17岁。因腹痛、呕血、黑便、全身皮肤紫癜半天,于1984年5月12日入院。入院前一天因上感肌注庆大霉素4万~u,2次/日。在当天晚上第二次肌注后约6小时,开始上腹部疼痛、呕吐、黑便、全身皮肤出现紫色斑片。腹痛为持续性,阵发性加
Gentamicin is a broad-spectrum antibiotic, clinical widely used in a variety of serious infectious diseases. However, serious side effects of gentamicin have been reported frequently in recent years, the most common allergic reactions. I met 1 case of gentamicin caused by severe allergic purpura with purpuric nephritis, the report is as follows, and combined with the literature to be discussed. Patient, male, 17 years old. Due to abdominal pain, hematemesis, melena, systemic skin purpura half a day, on May 12, 1984 admission. On the day before admission due to muscle injection of gentamicin 40,000 ~ u, 2 times / day. In the evening after the second intramuscular about 6 hours, began abdominal pain, vomiting, melena, purple patches on the body skin. Abdominal pain is persistent, paroxysmal plus