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目的研究复发性脑梗死的危险因素及临床特点。方法回顾性分析58例复发脑梗死和53例初发脑梗死患者的临床资料。结果复发组心肌受损率显著增高(p<0.01);女性、房颤、糖尿病、肥胖、高血压家族史和中风家族史者的发生率显著高于初发组(P<0.05～0.01);复发组血TC、TG、BS、纤维蛋白原、全血粘度(高切)、全血还原粘度(高切)、血浆粘度明显高于初发组(P<0.05～0.01),HDL-C则明显低于初发组(P<0.05);复发组死亡率与初发组有明显差异(p<0.05)。结论复发性脑梗死的治疗早期要注意预防心肌损伤。复发性脑梗死的可控危险因素主要是高血压病,血纤维蛋白原、TC水平、血浆粘度和全血高切还原粘度升高及HDL-C降低;而高血压病是复发与初发脑梗死患者共同的危险因素。
Objective To study the risk factors and clinical features of recurrent cerebral infarction. Methods The clinical data of 58 patients with recurrent cerebral infarction and 53 patients with primary cerebral infarction were retrospectively analyzed. Results The incidence of myocardial damage was significantly higher in relapse group (p <0.01). The incidence of atrial fibrillation, diabetes, obesity, family history of hypertension and family history of stroke were significantly higher than those in primary group (P <0.05-0.01). Plasma TC, TG, BS, fibrinogen, whole blood viscosity (high shear), whole blood viscosity (high shear) and plasma viscosity in relapse group were significantly higher than those in primary group (P <0.05-0.01) Significantly lower than the initial group (P <0.05); the mortality in the recurrence group was significantly different from the initial group (p <0.05). Conclusion Early treatment of recurrent cerebral infarction should pay attention to prevent myocardial injury. Controllable risk factors for recurrent cerebral infarction are mainly hypertension, fibrinogen, TC levels, plasma viscosity and whole blood high shear reduction viscosity and HDL-C decreased; and hypertension is a recurrence and primary brain Common risk factors for infarcted patients.