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中枢及周围交感神经系统在各种实验性高血压发生和维持中的作用,已得到越来越多的研究和证实。如:电刺激大鼠下丘脑,发现DOCA—盐大鼠交感神经活性及加压反应大于对照鼠;用酚妥拉明阻断α受体,DOCA—盐大鼠血压下降较对照鼠为著。6-羟多巴胺脑室注射,可预防DOCA—盐引起的血压升高及血浆去甲肾上腺素含量增加。此外,DOCA—盐高血压大鼠内脏交感神经冲动发放频率及血、尿儿茶酚胺含量均是增高的。亦有国内学者对葛根的药理作用进行了研究。发现葛根可增加动物的脑血流量,降低血
Central and peripheral sympathetic nervous system in a variety of experimental hypertension and maintain the role, has been more and more research and confirmation. For example, electrical stimulation of rat hypothalamus found that DOCA-salt rat sympathetic nerve activity and pressure response greater than the control mice; with phentolamine block α receptor, DOCA-salt rat blood pressure drop compared with the control mice. 6-OHDA intraventricular injection, can prevent DOCA-salt-induced hypertension and plasma norepinephrine levels. In addition, the frequency of visceral sympathetic nerve impulses and blood and urinary catecholamine levels were increased in DOCA-salt hypertensive rats. Some domestic scholars also studied the pharmacological effects of Pueraria. Pueraria is found to increase the animal’s cerebral blood flow, lower blood